NOT-OD-25-132 AI and Submission limits Guidance for NIH Applications

Previous notice:

 

Guidance:

NIH requirement of NOT-OD-25-132  Effective September, 2025, application limits. 

  • NIH will only accept up to six (6) new, renewal, resubmission, or revision applications per calendar year (excluding T activity codes and R13 conference grants) from an individual Principal Investigator/Program Director or Multiple Principal Investigator for all council rounds in a calendar year. NIH issued clarifications in FAQs 

  • NIH will not consider applications that are either substantially developed by AI, or contain sections substantially developed by AI. Applications must contain the original ideas of applicants. 

  • AI tools may be appropriate to assist in application preparation for limited aspects or in specific circumstances, but PIs are responsible for ensuring that all submissions reflect their own original work.  

 

NIH has released FAQ’s specifically addressing the application limit, clarifying how applications will be counted, and which type of applications are affected. 

 

PI will be responsible for checking in eRA Commons to monitor personal application submission limits. 

 

A new certification has been added to the eProposal approval/routing process including language:  

  • #8 I certify the final application is my own original ideas and is not substantially developed by AI, nor does it contain sections substantially developed by AI.  

Malign Foreign Talent Recruitment Program Certification

 

 

 

See Notice on where to direct Inquiries. 

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