The Patient-Centered Outcomes Research Institute (PCORI) has issued a request for applications for Partnering Research and Community Organizations for Comparative Clinical Effectiveness Research Across the Cancer Care Continuum. This program will fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects led by researcher and community partnerships to focus on advancing care and outcomes across different phases of the cancer care continuum. Proposed CER projects should inform health decisions for patients, caregivers and communities in the United States experiencing high burdens and practice variations in cancer care and outcomes.
PCORI is particularly interested in submissions that address the following Special Areas of Emphasis:
- Addressing barriers to recommended cancer screening and timely follow-up in the general population and among individuals at high risk of cancer.
- Improving the delivery of patient-centered, evidence-based care during cancer treatment.
- Addressing the post-treatment, follow-up care needs of cancer survivors.
Up to $12,000,000 direct costs will be awarded, for a project period of up to 5 years.
Eligibility criteria include:
- Proposals must include one PI from a research organization and one from a community organization to form the “core research-community partnership.”
- The two PIs must have previously collaborated with each other on research and/or health initiatives.
- The PI from the research organization must have prior experience in conducting community-partnered research studies.
- The community organization must have prior research experience and/or experience in implementing health initiatives in community settings.
- Beyond the core researcher-community partnership, applicants are required to engage with other organizations that represent the appropriate range of expertise and knowledge of the population of interest needed to carry out the award successfully, including organizations helpful for sustainability and scalability of the interventions.
Please see RFP for full criteria.
To Apply:
- This is an open RFP (UCSF may submit an unlimited number of applications).
- Follow application instructions in RFP, conferring with your Grants Officer as needed. Please notify your Grants Officer as soon as possible of your intention to apply to ensure that they will have enough time to support your application.
- LOI deadline is Tuesday, January 6, 2026. If you are invited to submit a full application, the deadline will be May 5, 2026.
For more information and to review complete application instructions and eligibility requirements, please visit https://www.pcori.org/funding-opportunities/announcement/cancer-partner-pfa-cycle-1-2026.